| Abstract |
The goal of this thesis was to improve embryo quality in assisted reproductive technologies by gaining more insight into human preimplantation embryo development and by improving in vitro culture conditions. To do so, we investigated an intriguing feature of the human preimplantation embryo, i.e. its mosaic nature, and the occurrence of mitotic aneuploidies. To improve in vitro culture conditions, we aimed to elucidate the effect of culture media on human preimplantation embryo development, and on the success rates of IVF/ICSI treatment.
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