DNA damage tolerance : from error free UV-damage bypass to mutagenesis of immunoglobulin genes

Authors	P. Langerak
Supervisors	J. Borst
Cosupervisors	H. Jacobs
Award date	01-02-2008
ISBN	9789057761737
Number of pages	103
Organisations	Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Table of contents Chapter I General introduction and scope Chapter II Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice Chapter III Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA Chapter IV A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification Chapter V The PCNA-Ub/Pol-eta complex: From antimutagenic damage bypass to mutagenic processing of modified Ig genes Chapter VI General discussion English summary / Nederlandse samenvatting Dankwoord Curriculum Vitae List of publications Cover
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