Thrombocidins and honey: mechanisms of action and optimization of antimicrobial activity

Authors	P.H.S. Kwakman
Supervisors	C.M.J.E. Vandenbroucke-Grauls
Cosupervisors	S.A.J. Zaat A.A. te Velde
Award date	01-07-2010
ISBN	9789081553513
Number of pages	150
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Chapter 5: © 2008 by the Infectious Diseases Society of America.
Language	English
Downloads	Thesis Front cover Title pages Contents Chapter 1: General introduction Chapter 2: Comparative nitrogen-15 heteronuclear backbone dynamic studies of the platelet chemokines NAP-2 and TC-1 in relation to antimicrobial activity Chapter 3: Structural elements for antimicrobial activity of thrombocidin-I and design of variants with enhanced activity Chapter 4: Treatment and prevention of Staphylococcus epidermidis experimental biomaterial-associated infection by Bactericidal Peptide 2 Chapter 5: Medical-grade honey kills antibiotic-resistant bacteria in vitro and eradicates skin colonization Chapter 6: How honey kills bacteria Chapter 7: Medical-grade honeys differ in their mechanism of bactericidal activity Chapter 8: Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens Chapter 9: General discussion and summary Samenvatting Dankwoord Curriculum vitae List of abbreviations Back cover Stellingen
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