Molecular identification in metabolomics using infrared ion spectroscopy
| Authors |
|
|---|---|
| Publication date | 13-06-2017 |
| Journal | Scientific Reports |
| Article number | 3363 |
| Volume | Issue number | 7 |
| Number of pages | 5 |
| Organisations |
|
| Abstract | Small molecule identification is a continually expanding field of research and represents the core challenge in various areas of (bio) analytical science, including metabolomics. Here, we unequivocally differentiate enantiomeric N-acetylhexosamines in body fluids using infrared ion spectroscopy, providing orthogonal identification of molecular structure unavailable by standard liquid chromatography/high-resolution tandem mass spectrometry. These results illustrate the potential of infrared ion spectroscopy for the identification of small molecules from complex mixtures. |
| Document type | Article |
| Note | With supplementary file |
| Language | English |
| Published at | https://doi.org/10.1038/s41598-017-03387-4 |
| Downloads |
Molecular
(Final published version)
Molecular supplement
(Other version)
|
| Permalink to this page | |