Pediatric gastroesophageal motility disorders From diagnosis to management

This thesis focuses on the diagnosis and management of most common acquired and congenital gastroesophageal motility disorders in children and tests that are used for the diagnosis or follow-up of these disorders.
In part I of this thesis, we evaluated diagnostic tests for the evaluation of pediatric gastroesophageal motility disorders. We calculated age-specific normal values of the Infant GastroEsophageal Reflux Questionnaire Revised (I-GERQ-R) and assessed the feasibility of high resolution manometry (HRM) and 24h pH Multichannel Intraluminal Impedance (pH-MII) testing in children.
In part II of this thesis, we discussed the management of two gastroesophageal motility disorders: esophageal atresia (EA) and achalasia in children. In achalasia, incidence, clinical course and quality of life were additionally evaluated.