The role of blood coagulation in cancer, inflammation and embryonic development

The role of blood coagulation in cancer, inflammation and embryonic development

Authors	L.W. Bruggemann
Supervisors	P.H. Reitsma
Cosupervisors	C.A. Spek H.H. Versteeg
Award date	27-06-2008
ISBN	9789064642593
Number of pages	198
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1 General overview and outline Cancer and metastasis Chapter 2 Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders Chapter 3 High FVIIa levels do not promote tumor metastasis Chapter 4 Metastasis promoting effects of thrombin inhibitors Chapter 5 Do anticoagulants affect colon cancer? Chapter 6 In vivo analysis of the antimetastatic effects of anticoagulants on murine cancer cell lines B16, K1735 and CT26 Inflammation Chapter 7 Role of coagulation FVIII in septic peritonitis assessed in hemophilic mice Chapter 8 Role of the FV Leiden mutation in septic peritonitis assessed in FV Leiden transgenic mice Chapter 9 Alternatively spliced tissue factor in mice: induction by Streptococcus Pneumoniae Chapter 10 Hyperglycemia accelerates arterial thrombus formation and attenuates the antithrombotic response to endotoxin in mice Development Chapter 11 The capacity to produce TF in all cells is not required for development although preference for TF bearing cells is evident in specific tissues Chapter 12 Differentiation of tissue factor knock-out embryoid bodies Summary Samenvatting List of publications Dankwoord Curriculum vitae Appendix Stellingen
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The role of blood coagulation in cancer, inflammation and embryonic development