Categorical methods for the interpretation of RNA profiles as cell type evidence and their limitations

Authors
Publication date 2015
Journal Forensic Science International. Genetics Supplement Series
Volume | Issue number 5
Pages (from-to) e305-e307
Organisations
  • Faculty of Science (FNWI) - Korteweg-de Vries Institute for Mathematics (KdVI)
  • Faculty of Science (FNWI) - Anton Pannekoek Institute for Astronomy (API)
Abstract Existing methods for the interpretation of RNA profiles as evidence for the presence of certain cell types aim for making categorical statements. Such statements limit the possibility to report the associated uncertainty. From a statistical point of view, a probabilistic approach is a preferable choice. Here, four popular existing methods for the interpretation of RNA evidence are discussed.
Document type Article
Note In special issue: Proceedings of the 26th International ISFG congress.
Language English
Published at https://doi.org/10.1016/j.fsigss.2015.09.121
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