Dyslipidemia; diagnosis and treatment

Thesis

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Titlepage

Inhoud

General introduction

Part I Diagnosis and assessment of genetic dyslipidemia

1 PREMATURE CORONARY DISEASE IN A PATIENT WITH TANGIER DISEASE: DIAGNOSIS AND THERAPY

2 AGE AND RESIDUAL CHOLESTEROL EFFLUX AFFECT HDL CHOLESTEROL LEVELS AND CORONARY ARTERY DISEASE IN ABCA1 HETEROZYGOTES

3 INCREASED ARTERIAL WALL THICKNESS IS CAUSED BY IMPAIRMENT IN ABCA1 DRIVEN CHOLESTEROL EFFLUX

4 THE DUTCH SCREENING PROGRAMME FOR FAMILIAL HYPERCHOLESTEROLEMIA - AN AUDIT-

PART II Aggressive therapy of dyslipidemia

1 DECLARING WAR ON UNDERTREATMENT: RATIONALE FOR AN AGGRESSIVE APPROACH TO LOWERING CHOLESTEROL

2 Additional efficacy of milligram-equivalent doses of atorvastatin over simvastatin

3 A LONG-TERM EFFICACY AND SAFETY OF ATORVASTATIN IN THE TREATMENT OF SEVERE TYPE III AND COMBINED DYSLIPIDEMIA

4 EFFICACY AND TOLERABILITY OF FLUVASTATIN IN A TITRATION DOSAGE REGIMEN IN HYPERLIPIDEMIC PATIENTS: result of a multi-center phase IV study

5 A COMPARISON OF THE EFFICACY AND TOLERABILITY OF TITRATE-TO-GOAL REGIMENS OF SIMVASTATIN VERSUS FLUVASTATIN: a randomized, double-blind study in adult patients at moderate to high risk for cardiovascular disease

6 EFFICACY AND SAFETY OF 80 MILLIGRAM SIMVASTATIN IN A NON-CONTROLLED LIPID CLINIC SETTING

7 Treatment of hyperlipidaemia with the statins: redefining what the statins can do

07. Treatment of hyperlipidaemia with the statins:

Part III Novel approaches to dyslipidemia

1 NEW ROLE FOR COMBINATION THERARY IN LIPID MANAGEMENT

2 EFFICACY AND SAFETY OF IMPLITAPIDE (BAY 13-9952), A MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR, IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA

3 THE EFFICACY OF CONCENTRATED N-3 FATTY ACIDS IN HYPERTRIGLYCERIDEMIA a comparison with gemfibrozil

4 CONSUMPTION OF TALL OIL DERIVED PHYTOSTEROLS IN A CHOCOLATE MATRIX SIGNIFICANTLY DECREASES PLASMA TOTAL AND LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVELS

5 CERIVASTATIN IN THE TREATMENT OF MIXED HYPERLIPIDEMIA: THE RIGHT STUDY

Summary

Samenvatting

Dankwoord

Curriculum vitae

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