Surgical treatment of choledochocystolithiasis

The studies presented in this thesis focus on surgical aspect of patients with complicated gallstone disease, with an emphasis on choledochocystolithiasis. Studies presented in the first part of this thesis investigated the influence of timing of laparoscopic cholecystectomy after endoscopic sphincterotomy on preoperative, intraoperative and postoperative outcome. In the second part we evaluated the effect of subspecialization of surgeons on the outcome of laparoscopic cholecystectomy and analyzed literature on the surgical approach of bile duct stones and in particular, laparoscopic bile duct exploration.