Balancing effector lymphocyte formation via CD27-CD70 interactions

Authors	R. Arens
Supervisors	R.A.W. van Lier M.H.J. van Oers
Award date	25-11-2003
Number of pages	127
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1 General Introduction Chapter 2 Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8 T cell formation. Chapter 3 Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNy-mediated B cell depletion Chapter 4 Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions. Chapter 5 CD95 maintains effector T cell homeostasis in chronic immune activation Chapter 6 B cells are crucial for both development and maintenance of the splenic marginal zone Chapter 7 Signaling through CD70 regulates B cell activation and lgG production Chapter 8 General Discussion Summary Samenvatting Publications Dankwoord Cover
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