| Abstract |
Cytosolic pH (pHc) is a crucial parameter in the cell because it is highly dynamic and its changes affect the function of all biomolecules containing weakly acidic or basic groups. Although it can influence most biological processes, our understanding of how pHc is controlled and what are the consequences of changes in pHc is rather limited. This thesis studied these two aspects of cytosolic pH signalling by dissecting the interaction between pHc and environmental signalling pathways in the budding yeast Saccharomyces cerevisiae.
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