The human immune response to Rh antigens

Authors	S.E. Dohmen
Supervisors	C.E. van der Schoot
Award date	18-03-2008
ISBN	9789090228549
Number of pages	158
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1 : General introduction Chapter 2 : Production of recombinant Ig molecules from antigen-selected single B cells and restricted usage of Ig-gene segments by anti-D antibodies Chapter 3 : The restricted use of IGHV3 superspecies genes in anti-Rh is not limited to hyperimmunized anti-D donors Chapter 4 : Anti-e found in a case of hemolytic disease of the fetus and newborn make use of the IGHV3 superspecies genes Chapter 5 : The analysis and quantification of a clonal B-cell response in a hyperimmunized anti-D donor Chapter 6 : The majority of anti-D-specific B cells in hyperimmunized anti-D donors are CD27-negative IgM-positive B cells Chapter 7 : Genetic factors influencing the anti-D immune response: HLA-DRB1*15 is associated with anti-D hyperimmunization Chapter 8 : General discussion and summary Chapter 9 Appendices : List of publications Chapter 9 Appendices : Co-authors affiliations Chapter 9 Appendices : Samenvatting Chapter 9 Appendices : Dankwoord Chapter 9 Appendices : Curriculum Vitae
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