Plasmacytoid dendritic cells: how to control the good, the bad, and the ugly at the molecular level

Authors	J.J. Karrich
Supervisors	H. Spits
Cosupervisors	B. Blom
Award date	19-02-2013
ISBN	9789461822314
Number of pages	192
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Front cover Title pages Table of contents Chapter 1: General introduction Chapter 2: The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the anti-apoptotic gene BCL2A1 Chapter 3: microRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells Chapter 4: microRNA-491 regulates Spi-B expression in plasmacytoid dendritic cells Chapter 5: Direct interaction between the Ets transcription factor Spi-B and NF-κB subunits regulates plasmacytoid dendritic cell activation and survival Chapter 6: The transcriptional regulator NAB2 reveals a two-step induction of TRAIL in activated plasmacytoid DCs Chapter 7: IL-21 stimulated human plasmacytoid dendritic cells secrete Granzyme B, which impairs their capacity to induce T cell proliferation Chapter 8: General discussion Summary Samenvatting Dankwoord List of publications
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