The role of mitochondria in cardioprotection

Authors	A. Heinen
Supervisors	M.W. Hollmann W.S. Schlack
Cosupervisors	N.C. Hauck B. Preckel
Award date	14-10-2008
Number of pages	177
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1: Introduction Chapter 2: Mitochondrial Ca2+-induced K+ influx increases respiration and enhances ROS production while maintaining membrane potential Chapter 3: Reverse electron flow-induced ROS production is attenuated by activation of mitochondrial Ca2+ sensitive K+ channels Chapter 4: The regulation of mitochondrial respiration by opening mKca channels is age-dependent Chapter 5: Helium-induced preconditioning in young and old rat heart - Impact of mKca channel activation Chapter 6: Helium-induced early preconditioning is abolished in obese Zucker rats in vivo Chapter 7: Helium-induced late preconditioning in the rat heart in vivo Chapter 8: Hyperglycaemia blocks Sevoflurane-induced postconditioning in the rat heart in vivo: Cardioprotection can be restored by blocking the mitochondrial permeability transition pore Chapter 9: Physiological levels of glutamine prevent morphine induced preconditioning in the isolated rat heart Chapter 10: Main conclusions and general discussion Summary Nederlandse samenvatting Acknowledgment About the author
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