Enantioselective syntheses of corynanthe alkaloids by chiral bronsted Acid and palladium catalysis.
| Authors |
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| Publication date | 2011 |
| Journal | Chemistry: A European Journal |
| Volume | Issue number | 17 | 49 |
| Pages (from-to) | 13680-13683 |
| Number of pages | 4 |
| Organisations |
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| Abstract |
Synergistic catalysis: Three indole alkaloids (−)-corynantheidine, (+)-corynantheine and (+)-dihydro-corynantheine were prepared following a short and common strategy based on the binol phosphoric acid catalyzed enantioselective Pictet-Spengler reaction, followed by closure of the final ring by an intramolecular Tsuji-Trost-type Pd-catalyzed allylic alkylation by using an α-ketoester-derived enolate as the nucleophile (see scheme). |
| Document type | Article |
| Note | PT: J; UT: MEDLINE:22069165 |
| Language | English |
| Published at |
https://doi.org/10.1002/chem.201103150
(Final published version)
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