High-level folate production in fermented foods by the B12 producer Lactobacillus reuteri JCM1112
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| Publication date | 2008 |
| Journal | Applied and Environmental Microbiology |
| Volume | Issue number | 74 | 10 |
| Pages (from-to) | 3291-3294 |
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| Abstract | We observed that Lactobacillus reuteri JCM1112 produces B12 and folate. However, the folate/B12 mass ratio found was far below that desired for human consumption (~170:1). We used metabolic engineering applying genetic and physiological approaches to improve this ratio and developed a generic and natural process that significantly increases folate production. |
| Document type | Article |
| Published at |
https://doi.org/10.1128/AEM.02719-07
(Final published version)
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