Toll-like receptors: tools, assays, and implications for in vitro pyrogen tests

Authors	R. Kikkert
Supervisors	L.A. Aarden
Award date	29-09-2009
ISBN	9789090245485
Number of pages	200
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Contents Chapter 1 General introduction Chapter 2 Recombinant expression of the ectodomain of human toll-like receptor 2 Chapter 3 Monoclonal antibody production against toll-like receptors Chapter 4 Activation of toll-like receptors 2 and 4 by Gramnegative periodontal bacteria Chapter 5 Effects of smoking on the ex vivo cytokine production in periodontitis Chapter 6 Cytokine induction by pyrogens: comparison of whole blood, mononuclear cells, and TLR-transfectants Chapter 7 Potentiation of toll-like receptor-induced cytokine production by (1-3)-β-D-glucans: implications for the monocyte activation test Chapter 8 Lipopolysaccharide activation of toll-like receptor 4 is potentiated by human serum and is enhanced in sepsis Chapter 9 T cell activation in whole blood induces IL-8, but no IL-6, and is dependent on IL-2, GM-CSF, and TNF production Chapter 10 Summary & general discussion Nederlandse samenvatting Dankwoord List of publications Curriculum vitae
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