New insights in the human thyroglobulin structure

Authors	S.A.R. van de Graaf
Supervisors	J.J.M. de Vijlder
Cosupervisors	C. Ris-Stalpers
Award date	10-10-2000
Number of pages	131
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: GEMO
Language	English
Downloads	Thesis Cover Titlepage CONTENTS ABBREVIATIONS Chapter 1 GENERAL INTRODUCTION Chapter 2 Up-to-date with the human thyroglobulin sequence. Chapter 3 Alternative polyadenylation cleavage sites in human thyroglobulin mRNA. Chapter 4 The screening for mutations in the thyroglobulin cDNA from six patients with congenital hypothyroidism. Chapter 5 A premature stopcodon in thyroglobulin mRNA results in familial goiter and moderate hypothyroidism. Chapter 6 The revised 8307 base pair coding sequence of human thyroglobulin transiently expressed in eukaryotic cells. Chapter 7 Human thyroglobulin can be expressed, glycosylated and iodinated in rabbit reticulocyte lysate. Chapter 8 GENERAL DISCUSSION SUMMARY SAMENVATTING voor niet-ingewijden PUBLICATIONS TOT SLOT... STELLINGEN Cover
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