Imaging in structural heart interventions
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| Award date | 11-11-2024 |
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| Number of pages | 410 |
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| Abstract |
This PhD thesis focuses on imaging in structural heart interventions.
Part I specifically focuses on imaging in left ventricular (LV) interventions for ischemic heart failure. It provides technical and imaging considerations for hybrid transcatheter and minimally invasive left ventricular reconstruction (LVR). Additionally, it presents the results of the INTERSECT study and introduces a novel imaging methodology (called inward displacement) for evaluating improvements in regional LV function. A review of ventricular volume reduction in ischemic cardiomyopathy and future prospects for LVR are also discussed. Part II focuses on optimizing aortic valve procedures through preprocedural planning. The GUIDE-TAVI and GUIDE-SAVR trials are key studies exploring the impact of imaging on procedural outcomes, aiming to reduce adverse outcomes like paravalvular regurgitation and stroke. Part III discusses imaging in mitral valve interventions, including minimally invasive mitral valve repair and echocardiographic outcomes in the surgical treatment of hypertrophic obstructive cardiomyopathy. Part IV explores transcatheter tricuspid valve interventions, highlighting the role of imaging in patient selection and procedural guidance. Finally, Part V focuses on imaging in aortic interventions performed after previous cardiac and/or aortic surgery, specifically demonstrating the potential of transcatheter thoracic aortic pseudoaneurysm closure guided by preprocedural 3D reconstructions. |
| Document type | PhD thesis |
| Language | English |
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