Supplying the demand for granulocytes: function and gene expression profile of mobilized neutrophils

Authors	A.A. Drewniak
Supervisors	T.W. Kuijpers D. Roos
Award date	01-06-2010
ISBN	9789490371180
Number of pages	205
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: Introduction and scope of the thesis Chapter 2: Granulocyte transfusions: randomization after all? Chapter 3: Granulocyte concentrates: prolonged functional capacity during storage in the presence of phenotypic changes Chapter 4: Changes of gene expression of granulocytes during in vivo G-CSF/dexamethasone mobilization for transfusion purposes Chapter 5: Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-3 Chapter 6: TLR responses in IRAK-4 deficient neutrophils Chapter 7: Toll-like Receptor-induced reactivity and strongly potentiated IL-8 production in granulocytes mobilized for transfusion purposes Chapter 8: Mobilization of granulocytes with G-CSF/dexamethasone alters their ability to produce macrophage inflammatory proteins Chapter 9: Summary and general discussion Samenvatting Podsumowanie Curriculum vitae Acknowledgements List of publications Colour pictures
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