Diacylglycerol kinase
| Authors | |
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| Publication date | 2010 |
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| Book title | Lipid signaling in plants |
| ISBN |
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| Series | Plant cell monographs, 16 |
| Pages (from-to) | 107-114 |
| Number of pages | 330 |
| Publisher | Heidelberg: Springer |
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| Abstract |
Diacylglycerol kinase (DGK, EC 2.7.1.107) is a lipid kinase that phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). DGK belongs to a well-conserved family of proteins found in diverse species, such as Saccharomyces cerevisiae, Drosophila melanogaster, Caenorhabditis elegans, mammals, plants, and bacteria (Merida et al. Biochem J 409:1-18, 2008). In eukaryotes, DGK can be activated in response to various stimuli, and its product PA is emerging as a novel lipid second messenger (Munnik, Trends Plant Sci 6:227-233, 2001; Testerink and Munnik, Trends Plant Sci 10:368-375, 2005). Despite similarities to the mammalian system, plant DGKs display several distinctive features.
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| Document type | Chapter |
| Language | English |
| Published at | https://doi.org/10.1007/978-3-642-03873-0_7 |
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