Chiral-at-Ruthenium Catalyst Does the Job: Access to Enantioenriched 2-Imidazolidinones
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| Publication date | 06-08-2020 |
| Journal | Chemical Science |
| Volume | Issue number | 6 | 8 |
| Pages (from-to) | 1851-1853 |
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| Abstract | Catalytic and enantioselective ring-closing C(sp3)‒H amidation of urea derivatives has been unexplored. In this issue of Chem, Meggers and co-workers address this challenge by using a chiral-at-ruthenium catalyst to obtain cyclic 2-imidazolidinones in a highly enantioselective manner. The latter can be converted to chiral vicinal diamines without appreciable loss of enantiopurity. |
| Document type | Article |
| Language | English |
| Published at | https://doi.org/10.1016/J.CHEMPR.2020.07.005 |
| Downloads |
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