Structure of a novel multidrug resistance modulator, irciniasulfonic acid, isolated from a marine sponge, Ircinia sp.
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| Publication date | 2001 |
| Journal | Tetrahedron Letters |
| Volume | Issue number | 42 |
| Pages (from-to) | 3335-3337 |
| Number of pages | 3 |
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| Abstract | Irciniasulfonic acid was obtained from a marine sponge of Ircinia sp. Spectroscopic and chemical analyses revealed its structure consists of three different kinds of acids, i.e. common fatty acids, a novel unsaturated branched C-10 fatty acid and an isethionic acid. Irciniasulfonic acid and deacyl irciniasulfonic acid reverse multidrug resistance in human carninoma cells due to overexpression of membrane glycoprotein. |
| Document type | Article |
| Published at |
https://doi.org/10.1016/S0040-4039(01)00426-9
(Final published version)
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