Cytomegalovirus-specific T-cell dynamics in HIV infection

Authors	C. Bronke
Supervisors	F. Miedema
Cosupervisors	D. van Baarle K. Tesselaar
Award date	24-03-2005
ISBN	9090191712 9789090191713
Number of pages	153
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Downloads	Thesis Cover Titlepage CONTENTS Chapter 1 General Introduction Chapter 2 Dynamics of CMV-specific T cells in HIV-1-infected individuals progressing to AIDS with CMV end-organ disease Chapter 3 Progression to CMV end-organ disease in HIV-1-infected individuals despite abundance of highly differentiated CMV-specific CD8+ T cells Chapter 4 Direct ex vivo detection of HLA-DR3-restricted cytomegalovirus- and Mycobacterium tuberculosis-specific CD4+ T cells Chapter 5 Loss of CMV-specific CD4+ T-cell cytokine production and proliferative capacity precedes progression to HIV-related CMV end-organ disease Chapter 6 In HIV-1-infected children CMV rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27- T cells Chapter 7 Characterisation of virus-specific CD8+ effector T cells in the course of HIV-1 infection: longitudinal analyses in slow and rapid progressors Chapter 8 General Discussion Summary Samenvatting DANKWOORD Cover
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