Treatment strategies and risk stratification in acute coronary syndromes

Thesis

Cover

Title pages

Table of contents

List of publications

Chapter 1: General introduction and outline of the thesis

Chapter 2: 5-year clinical outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) trial: A randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary syndrome

Chapter 3: Long-term outcome of a routine versus selective invasive strategy in patients with non-ST-segment elevation acute coronary syndrome: A meta-analysis of individual patient data

Chapter 4: Effects of age on long-term outcomes after a routine invasive or selective invasive strategy in patients presenting with non-ST segment elevation acute coronary syndromes: A collaborative analysis of individual data from the FRISC II/ICTUS/RITA-3 (FIR) trials

Chapter 5: Timing of angiography with a routine invasive strategy and long-term outcomes in non-ST-elevation acute coronary syndrome: A collaborative analysis of individual patient data from the FRISC II, ICTUS, and RITA-3 trials (FIR)

Chapter 6: Invasive strategies and outcomes for non-ST-segment elevation acute coronary syndromes: A twelve-year experience from SWEDEHEART

Chapter 7: Long-term cardiovascular mortality after procedure-related or spontaneous myocardial infarction in patients with non-ST-segment elevation acute coronary syndrome: A collaborative analysis of individual patient data from the FRISC II, ICTUS, and RITA-3 trials (FIR)

Chapter 8: Prognostic relevance of PCI-related myocardial infarction

Chapter 9: Usefulness of the admission electrocardiogram to predict long-term outcomes after non-ST-elevation acute coronary syndrome (from the FRISC II, ICTUS, and RITA-3 [FIR] Trials)

Chapter 10: Growth-differentiation factor 15 for long-term prognostication in patients with non-ST-elevation acute coronary syndrome: An invasive versus conservative treatment in unstable coronary syndromes (ICTUS) substudy

Chapter 11: Multiple biomarkers at admission significantly improve the prediction of mortality in patients undergoing primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction

Chapter 12: Survival of patients after ST-elevation myocardial infarction: External validation of a predictive biomarker model

Chapter 13: Multiple biomarkers at admission are associated with angiographic, electrocardiographic and imaging cardiovascular mechanistic markers of outcomes in patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction

Summary of the thesis

Samenvatting van het proefschrift

Authors and affiliations

Dankwoord / Acknowledgements

Curriculum vitae