A new entry to adenosine analogues via purine nitration - Combinatorial synthesis of antiprotozoal agents and adenosine receptor ligands

Thesis

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Titlepage

CONTENTS

1 Introduction

2 Solid phase synthesis of 2,N6-disubstituted adenosine analogues

3 Solid phase synthesis of di- and trisubstituted 5'-carboxamidoadenosine analogues

4 Conformationally restricted adenosine analogues

5 Antiprotozoal evaluation of adenosine analogues

6 The mechanism of purine nitration

Summary

Samenvatting

Nawoord

Cover