Host-pathogen interactions during (myco)bacterial respiratory tract infections

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Contents

1 Host-pathogen Interactions During (Myco)bacterial Respiratory Tract infections, General Introduction

2 The MyD88 dependent but not the MyD88 independent pathway of Toll-like receptor 4 signaling is important in clearing non-typeable Haemophilus influenzae from the mouse lung

3 Differential roles of CD14 and Toll-like Receptors 4 and 2 in murine Acinetobacter pneumonia

4 Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense

5 CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis

6 Non-mannose-capped lipoarabinomannan induces lung inflammation via Toll-like receptor 2

7 Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for the defense against pulmonary Streptococcus pneumoniae infection

8 Mice lacking murine SIGNR1 have a normal host defense against Mycobacterium tuberculosis

9 CD4' cells play a limited role in murine lung infection with Mycobacterium kansasii

10 Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract

11 CD27 is important in the early immune response to Mycobacterium tuberculosis infection but does not affect outcome

12 CD27 deficient mice have an improved defense against Streptococcus pneumoniae pneumonia

13 Pulmonary Mycobacterium tuberculosis infection in leptin deficient ob/ob mice

14 Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice

15 General Summary and Discussion Samenvatting List of Publications Dankwoord Curriculum vitae Color figures

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