From LPA signaling to polycomb : oncogenic cooperations revealed by genetic screens and dynamics and recruitment of polycomb group proteins

Authors	P. Taghavi
Supervisors	M.M.S. van Lohuizen
Award date	09-04-2009
ISBN	9789075575170
Number of pages	147
Publisher	s.l: Nederlands Kanker Instituut / Antoni Van Leeuwenhoek ziekenhuis
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: General introduction : Cooperative oncogenic alterations involved in tumorigenesis and Bmi1, the founding member of mammalian Polycomb group proteins Chapter 2: In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation Chapter 3: Search for novel oncogenes that cooperate with activated Ras in cellular transformation using in vitro genetic screens Chapter 4: Association of Bmi1 with Polycomb bodies is dynamic and requires PRC2/Ezh2 and the maintenance DNA methyltransferase Dnmt1 Chapter 5: Summary and general discussion Nederlandse samenvatting Acknowledgments Curriculum vitae List of publications
Permalink to this page

Back

UvA-DARE