Human Adult Neurogenesis: Evidence and Remaining Questions

Open Access
Authors
  • G. Kempermann
  • F.H. Gage
  • L. Aigner
  • H. Song
  • M.A. Curtis
  • S. Thuret
  • H.G. Kuhn
  • S. Jessberger
  • P.W. Frankland
  • H.A. Cameron
  • E. Gould
  • R. Hen
  • D.N. Abrous
  • N. Toni
  • A.F. Schinder
  • X. Zhao
  • P.J. Lucassen ORCID logo
  • J. Frisén
Publication date 05-07-2018
Journal Cell Stem Cell
Volume | Issue number 23 | 1
Pages (from-to) 25-30
Organisations
  • Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Abstract

Renewed discussion about whether or not adult neurogenesis exists in the human hippocampus, and the nature and strength of the supporting evidence, has been reignited by two prominently published reports with opposite conclusions. Here, we summarize the state of the field and argue that there is currently no reason to abandon the idea that adult-generated neurons make important functional contributions to neural plasticity and cognition across the human lifespan.

Document type Review article
Language English
Published at https://doi.org/10.1016/j.stem.2018.04.004
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1-s2.0-S1934590918301668-main (Final published version)
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