Mouse models for the human hereditary cancer syndromes retinoblastoma and neurofibromatosis type 2

Authors	E.C. Robanus Maandag
Supervisors	A.J.M. Berns
Cosupervisors	H.P.J. Riele
Award date	16-12-1999
Number of pages	127
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1: Introduction. Chapter 2: Requirement for a functional Rb-1 gene in murine development. Chapter 3: Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice. Chapter 4: p107 is a suppressor of retinoblastoma development in pRb-deficient mice. Chapter 5: Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein. Chapter 6: Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Summary Samenvatting Abbreviations Publications Dankwoord Curriculum Vitae Cover
Permalink to this page

Back

UvA-DARE