Novel biomarkers to guide therapy in chronic inflammatory diseases
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| Award date | 20-12-2023 |
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| Number of pages | 280 |
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| Abstract | In this thesis, we focused on the role of the epigenetic modifications in Inflammatory Bowel Disease (IBD) and other immune mediated diseases such as rheumatoid arthritis. In particular, we elaborated on aberrant DNA methylation and investigated its potential to predict therapy response to biological treatment. Furthermore, we explored other novel biomarkers to biological response with microbial signatures and single cell transcriptomics in IBD. |
| Document type | PhD thesis |
| Language | English |
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