Care for women across critical junctures during the reproductive years Reproductive choices, pregnancy and menopause

Open Access
Authors
  • A.Y.A.M. Reilingh
Supervisors
  • I.G.M. van Valkengoed
  • S.J. Gordijn
Cosupervisors
  • J.M. van Ditzhuijzen
  • R.J. Burger
Award date 4 November 2026
ISBN
  • 9789465377667
Number of pages 232
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract
Reproductive milestones that are specific to women can be seen as critical junctures that shape women’s lives and may offer pragmatic opportunities for care and prevention. This thesis investigates how several of these reproductive milestones can be used to improve women’s health trajectories, both during the reproductive years and in relation to later cardiovascular and renal disease.
Part I examines reproductive choices. This focuses on contraceptive behaviour preceding unintended pregnancies and motivations for abortion. The studies show that women often navigate negative experiences with hormonal contraception, rely on less effective methods, and make decisions within complex relational and socioeconomic contexts. Non judgmental, personalized counselling that builds trust and acknowledges these contexts is essential.
Part II explores cardiovascular risk after pregnancy complications. The thesis shows that pregnancy complications largely reveal an already adverse cardiovascular risk profile. Postpartum risk management can be strengthened through active outreach, culturally tailored follow up, and multidisciplinary care.
Part III focuses on early menopause in relation to the risk of long term cardiovascular and kidney disease. Adding early menopause to currently used cardiovascular risk screening criteria did not improve the detection of women at high risk. Early menopause was not consistently associated with chronic kidney disease in the overall multiethnic population, but associations varied across ethnic groups.
Overall, the thesis argues that recognizing reproductive milestones as recurring critical junctures can help align counselling, outreach, and preventive care, supporting more equitable health and wellbeing for diverse groups of women.
Document type PhD thesis
Language English
Downloads
Thesis (complete) (Embargo up to 4 November 2028)
Chapter 3: Beyond singular reasons. Motivations for abortion in constellation: A Dutch mixed methods study (Embargo up to 4 November 2028)
Chapter 4: The associations of pregnancy complications with changes in the cardiovascular risk profile around pregnancy- a HELIUS-Perined study (Embargo up to 4 November 2028)
Chapter 7: The association between self-reported early menopause and change in kidney function in a multi-ethnic population. The HELIUS Study (Embargo up to 4 November 2028)
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