Local immunomodulatory gene therapy for Sjögren’s syndrome

Thesis

Cover

Title pages

Table of contents

Chapter 1: General introduction

Chapter 2: Advances in vector-mediated gene transfer

Chapter 3: A recombinant adenoviral vector encoding functional vasoactive intestinal peptide

Chapter 4: Local adeno-associated virus-mediated interleukin-10 gene transfer has disease-modifying effects in a murine model of Sjögren's syndrome

Chapter 5: Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjögren’s syndrome

Chapter 6: Local delivery of IκBα super repressor cDNA leads to disease-modifying effects in the NOD mouse model for Sjögren’s syndrome

Chapter 7: NOD mouse model for Sjögren’s syndrome : lack of longitudinal stability

Chapter 8: Summary and discussion

General summary

Samenvatting [Dutch]

List of abbreviations