Transcriptional control of human plasmacytoid dendritic cell and B cell differentiation

Authors	H. Schmidlin
Supervisors	H. Spits C.H. Uittenbogaart
Cosupervisors	B. Blom
Award date	07-10-2008
Number of pages	189
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title page Contents Chapter 1: General introduction Chapter 2: Development of human plasmacytoid dendritic cells depends on the combined action of E2-2 and Spi-B Chapter 3: Regulation of human plasmacytoid dendritic cell maturation and function by Spi-B Chapter 4: Identification of potential Spi-B targets in the plasmacytoid dendritic cell lineage by microarray analysis Chapter 5: Stimulated plasmacytoid dendritic cells impair human T cell development Chapter 6: STAT5 activation in human B cells prevents class switch recombination through regulation of AID Chapter 7: STAT3-mediated upregulation of BLIMP1 is coordinated with BCL6 downregulation to control human plasma cell differentiation Chapter 8: Spi-B Inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression Chapter 9: General discussion Summary Samenvatting List of publications Dankwoord
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