From progenitor cell to immune cell : cytokines and transcription factors in human hematopoietic development

Authors	W. Dontje
Supervisors	H. Spits
Cosupervisors	B. Blom
Award date	03-10-2008
Number of pages	188
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title page Contents Chapter 1: Introduction Chapter 2: Role of IL-7 on human lymphoid development and homeostasis in Chapter 3: Delta-like1- induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T cell lineage decision through control of GATA-3 and Spi-B Chapter 4: Stimulated plasmacytoid dendritic cells impair human T cell development Chapter 5: Synergy between IL-15 and Id2 promotes thymic progenitor cells to develop into NK cells Chapter 6: Notch4 and IL-7 signaling cooperate in the development of human IL-7Rα+CD56+ NK cells Chapter 7: FLT3-ITD mutations impair plasmacytoid dendritic cell development through aberrant STAT5 signaling Chapter 8: Discussion Summary Nederlandse samenvatting Dankwoord List of publications
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