From conception to cognitive decline

From conception to cognitive decline How the prenatal environment may shape late-life brain health

Authors	A. Boots
Supervisors	T.J. Roseboom
Cosupervisors	S.R. de Rooij
Award date	06-09-2024
ISBN	9789465061559
Number of pages	292
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis (complete) Front matter Chapter 1: General introduction Chapter 2: Shaping the risk for late-life neurodegenerative disease: A systematic review on prenatal risk factors for Alzheimer’s disease-related volumetric brain biomarkers Chapter 3: Longitudinal changes in late-life brain health after prenatal exposure to the Dutch famine Chapter 4: Brain aging after prenatal undernutrition: Longitudinal BrainAGE estimations in the Dutch famine birth cohort Chapter 5: Sex-specific effects of prenatal undernutrition on resting-state functional connectivity in the human brain at age 68 Chapter 6: Prenatal famine exposure and late-life functional brain network connectivity: A longitudinal study Chapter 7: Do prenatal factors shape the risk for dementia?: A systematic review of the epidemiological evidence for the prenatal origins of dementia Chapter 8: Exposure to the Dutch famine in early gestation and cognitive function and decline in older age Chapter 9: Brain activity during Stroop task performance at age 74 after exposure to the Dutch famine during early gestation Chapter 10: General discussion English summary; Nederlandse samenvatting; List of publications; PhD portfolio; Dankwoord
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