Kindlin-3 in hematopoietic integrin activation: Absence in leukocyte adhesion deficiency type III

Authors	E. van de Vijver
Supervisors	T.W. Kuijpers
Cosupervisors	T.K. van den Berg D. Roos
Award date	27-06-2013
ISBN	9789461822888
Number of pages	155
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: General introduction Chapter 2: LAD-1/variant syndrome is caused by mutations in FERMT3 Chapter 3: Leukocyte adhesion deficiencies Chapter 4: Hematologically important mutations: Leukocyte adhesion deficiency (first update) Chapter 5: Kindlin-3-independent adhesion of neutrophils from leukocyte adhesion deficiency type III (LAD-III) patients Chapter 6: Activation of β2 integrins on human neutrophils requires recruitment of kindlin-3 to the plasma membrane: A role for the PH and PTB domain of kindlin-3 Chapter 7: Defects in Glanzmann thrombasthenia and LAD-III (LAD-1/v) syndrome: The role of integrin β1 and β3 in platelet adhesion to collagen Chapter 8: Kindlin-3 regulates erythroblast adhesion and expansion Chapter 9: Summary and general discussion Nederlandse samenvatting List of publications Dankwoord / Acknowledgements
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