Digital health in motion Innovations in wearable rhythm monitoring and remote cardiac care

Open Access
Authors
  • N.J. van Steijn
Supervisors
  • R.E. Knops
  • A.A.M. Wilde
Cosupervisors
  • M.M. Winter
  • G.A. Somsen
Award date 23 October 2026
ISBN
  • 9789465347042
Number of pages 194
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract
Cardiovascular care is facing increasing pressure due to population ageing, chronic disease, and growing demand for specialist care. Wearable technologies offer new opportunities to monitor cardiovascular health beyond the hospital and to support more continuous, patient-centred models of care. This thesis investigates how such technologies can be integrated into cardiovascular care and applied to arrhythmia detection, monitoring of high-risk patients, and physiological assessment.
In the EQUAL trial, six months of Apple Watch monitoring in older adults at increased risk of stroke resulted in approximately four times more newly detected atrial fibrillation and earlier diagnosis than standard care. Expert review of smartwatch ECGs labelled unclassified by the algorithm also identified clinically relevant arrhythmias beyond atrial fibrillation.
A ring-type photoplethysmography wearable detected loss of arterial pulse flow during induced ventricular arrhythmias with high sensitivity, supporting the potential for future automated cardiac arrest detection. A systematic review identified female sex and arrest at home as consistent determinants of unwitnessed out-of-hospital cardiac arrest.
In patients with congenital long QT syndrome, mobile QTc assessment was feasible using handheld and wearable ECG devices, although device-specific validation against the standard 12-lead ECG remains recommended.
Finally, wearable-derived heart rate variability measurements showed favourable changes during white noise and classical music.
Overall, this thesis shows that wearables, when carefully validated and embedded in clinical workflows with expert review, can support earlier diagnosis, remote monitoring, and more proactive cardiovascular care.
Document type PhD thesis
Note Please note that the Acknowledgements and About the author sections are not included in thesis downloads.
Language English
Downloads
Thesis (Embargo up to 23 October 2028)
Chapter 5: Determinants of unwitnessed out-of-hospital cardiac arrest: A systematic review (Embargo up to 23 October 2028)
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