Chemoenzymatic Halocyclization of γ,δ‐Unsaturated Carboxylic Acids and Alcohols

Open Access
Authors
  • S.H.H. Younes
  • F. Tieves
  • D. Lan
  • Y. Wang
  • P. Süss
  • H. Brundiek
  • R. Wever
  • F. Hollmann
Publication date 09-01-2019
Journal ChemSusChem
Volume | Issue number 13 | 1
Pages (from-to) 97-101
Number of pages 5
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract A chemoenzymatic method for the halocyclization of unsaturated alcohols and acids by using the robust V-dependent chloroperoxidase from Curvularia inaequalis (CiVCPO) as catalyst has been developed for the in situ generation of hypohalites. A broad range of halolactones and cyclic haloethers are formed with excellent performance of the biocatalyst.
Document type Article
Note With supplementary file
Language English
Published at https://doi.org/10.1002/cssc.201902240
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cssc.201902240 (Final published version)
Supplementary materials
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