Adhesion molecules in lymphoma cell migration and metastasis. The role of the beta1 integrin cytoplastic domain

Thesis

Cover

Titlepage

Contents

Chapter 1 Integrins and associated molecules: signaling pathways in cell adhesion and migration Introduction

Chapter 2 Targeted disruption of CD44 in MDAY-D2 lymphosarcoma cells has no effect on subcutaneous growth or metastatic capacity

Chapter 3 Targeted disruption of the β1 integrin gene in a lymphoma cell line greatly reduces metastatic capacity

Chapter 4 Cytoplasmic domain mutants of β1 integrin, expressed in β1 -knockout lymphoma cells, have distinct effects on adhesion, invasion and metastasis

Chapter 5 The integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the RhoA effector ROCK at the cell membrane: possible implications for cell spreading and migration

Summary

Samenvatting

Dankwoord

Curriculum Vitae

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