Immune activation and lineage fate decisions: Inducing a shift of program

Authors	S.F.W.M. Libregts
Supervisors	R.A.W. van Lier
Cosupervisors	M.A. Nolte
Award date	26-09-2013
ISBN	9789461918529
Number of pages	199
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis Cover Title pages Table of contents Chapter 1: General introduction Chapter 2: Function of CD27 in T cell differentiation Chapter 3: CD27 expression and function during ontogeny of the hematopoietic system Chapter 4: Chronic IFN-γ production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis Chapter 5: IFN-γ induces a Noxa-dependent alternative pathway of programmed cell death in erythroid precursors Chapter 6: Differential effects of IFN-γ on erythropoiesis in bone marrow versus spleen Chapter 7: General discussion Chapter 8: Nederlandstalige samenvatting List of publications PhD portfolio Curriculum vitae Acknowledgements
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