- Host-pathogen interactions during melioidosis. When the bug meets its host
T. van der Poll
- Award date
- 10 June 2016
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
Melioidosis, caused by the bacterium Burkholderia pseudomallei, is an important cause of community-acquired sepsis and related death in Southeast Asia and Northern Australia. After recognition of the invaded bacterium the host’s immune system elicits a powerful immune response, essential to eliminate the microorganism. However, an overwhelming systemic inflammatory response can lead to detrimental tissue damage and death. Keeping the balance between pro- and anti-inflammatory processes is therefore crucial for survival of the host.
This thesis presents an overview of experimental studies on the role of innate immune receptors and specific proteins during melioidosis.
- Research conducted at: Universiteit van Amsterdam
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.