- The microbiome and its therapeutic potential in inflammatory bowel diseases
G.R.A.M. D' Haens
- Award date
- 22 January 2016
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
While the etiology of inflammatory bowel diseases (IBD) remains unclear, there is substantial evidence for the link between the microbiota and the pathogenesis of IBD. Interest for the application of Fecal Microbiota Transplantation (FMT) increases, especially now the insight in the intestinal microbiota in health and disease is growing rapidly by the possibility to study the microbiota composition and function, and their dynamics, using a wide variety of culture-independent approaches.
This thesis describes the microbiota composition in inflammatory bowel diseases and the impact of FMT on patients with ulcerative colitis and their microbiota.
- Research conducted at: Universiteit van Amsterdam
Thesis (complete) (Embargo until 22 January 2018)
Chapter 2: Rising prevalence and burden of disease of inflammatory bowel disease in a population-based cohort in The Netherlands (Embargo until 22 January 2018)
Chapter 7: Fecal transplantation in ulcerative colitis: microbiota shifts and signatures that determine long-term success of therapy (Embargo until 22 January 2018)
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