- Risk factors and prognostic models for perinatal asphyxia at term
A. Abu Hanna
- Award date
- 18 December 2015
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
This thesis will focus on the risk factors and prognostic models for adverse perinatal outcome at term, with a special focus on perinatal asphyxia and obstetric interventions during labor to reduce adverse pregnancy outcomes. For the majority of the studies in this thesis we were allowed to use data of the Netherlands Perinatal Registry (PRN). The PRN consists of national population-based data containing information on pregnancies, deliveries and (re)admissions until 28 days after birth. For one study the database of the Foundation Perinatal Audit in the Netherlands (PAN) was used.
Aim of this thesis: 1. To identify risk factors for asphyxia related morbidity and mortality at term singleton pregnancies. 2. To investigate the practice variance according to obstetric interventions and explore the association between variation in caesarean delivery rates with maternal and neonatal outcomes. 3. To develop prognostic models to predict adverse neonatal and pregnancy outcomes at term.
- Research conducted at: Universiteit van Amsterdam
Thesis (complete) (Embargo until 18 December 2017)
Chapter 3: Are higher rates of obstetric interventions associated with a better neonatal outcome? A population wide cohort study (Embargo until 18 December 2017)
Chapter 6: Maternal and neonatal risk factors for asphyxia related perinatal mortality at term (Embargo until 18 December 2017)
Chapter 7: Predictive capacity of the five individual components of the 5 minute Apgar score on neonatal mortality and morbidity in term infants (Embargo until 18 December 2017)
Chapter 8: The development of a clinical prediction model to support clinicians in the simultaneous assessment of the risks of failure to progress and fetal asphyxia in term pregnancies (Embargo until 18 December 2017)
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