- HIPEC treatment of peritoneal carcinomatosis in colorectal and gastric cancer
B. van Ramshorst
- Award date
- 6 November 2015
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
This thesis focuses on the treatment of peritoneal metastases of gastric and colorectal cancer, specifically using cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). A large part of this thesis is based on retrospective analysis of patients treated with CRS + HIPEC in the St. Antonius hospital, Nieuwegein, and Catherina Hospital, Eindhoven. By combining the patients’ databases of both hospitals, we were offered a large unique set of colorectal cancer patients treated with CRS + HIPEC. This made it possible to establish statistically significant conclusions regarding specific subgroups of patients with peritoneal carcinomatosis of colorectal cancer.
Part 1 is concentrated on the early treatment of peritoneal metastases in gastric and colorectal cancer.
Part 2 of this thesis explores the current borders of peritoneal carcinomatosis treatment with cytoreductive surgery and HIPEC.
Part 3 is aimed at exploring the outcome of patients in whom the treatment of peritoneal carcinomatosis with CRS + HIPEC was deemed not feasible and the outcome of patients presenting with recurrent disease following a previous HIPEC procedure.
- Research conducted at: Antoniusziekenhuis Nieuwegein
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