- Reflux, belching, rumination and their interrelationships
- Award date
- 28 May 2015
- Number of pages
- Document type
- PhD thesis
- Faculty of Medicine (AMC-UvA)
Patients with gastroesophageal reflux disease (GERD), excessive belching and the rumination syndrome are all characterized by troublesome symptoms due to retrograde flow of material (liquid, solid and/or gaseous) through the esophagus. In this thesis, we present a number of studies in which we provide novel insights into the pathophysiology, diagnosis and treatment of these diseases.
We demonstrate in this thesis that GERD, belching and rumination are three distinct disorders but with many interrelationships. The studies described in this thesis contribute to a better identification of patients in whom the treatment can be aimed at the mechanism underlying their belching complaints or complaints of regurgitation. Moreover, these studies could also result in new treatment modalities for patients with "true" GERD such as prokinetics or anxiolytics or affect the treatment for patients in whom anti-reflux surgery appears to have failed.
- Research conducted at: Universiteit van Amsterdam
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.