- A technical note on challenge tests in human volunteers for multidimensional phenotyping
- Chemometrics and Intelligent Laboratory Systems
- Pages (from-to)
- Document type
- Faculty of Science (FNWI)
- Swammerdam Institute for Life Sciences (SILS)
Challenge tests are used to reveal the adaptability and resilience of humans to get insight in their health. When contrasting challenge tests are used, various forms of adaptability can be tested and this gives a multidimensional view on the health of these individuals. Here we introduce a methodology to describe the similarities and differences on how individuals are positioned in the health space based on the responses to different challenge tests. Results show that anabolic and catabolic challenges differentiate healthy subjects in rather different ways. Considering these results we hypothesize that combining challenge tests can improve the understanding of the underlying multidimensional phenotype.
- go to publisher's site
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.