D. de Wied
A.C. Frankhuijzen Sierevogel
- Plasma arginine vasopressin and motor activity in major depression.
- Biological Psychiatry
- Volume | Issue number
- 43 | 3
- Pages (from-to)
- Document type
- Faculty of Social and Behavioural Sciences (FMG)
- Psychology Research Institute (PsyRes)
Investigated the relationship between the mean plasma concentration of arginine vasopressin (AVP), oxytocin (OT) and clinically rated psychomotor retardation. 48 inpatients and outpatients with major depression (aged 22-77 yrs) and 30 healthy controls (aged 19-73 yrs) participated. Plasma AVP and OT concentrations were measured 3 times a day (8:00, 16:00, and 23:00 hrs) and day and nighttime wrist activity were measured during a period of 5 consecutive days and nights. Principal component analysis revealed 3 components of motor activity: motor activity during wakefulness, motor activity during sleep, and the awake/sleep time ratio. In patients and controls an inverse relationship between plasma AVP concentrations and motor activity during wakefulness was found. Patients with elevated AVP plasma levels showed increased motor activity during sleep.
- go to publisher's site
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.