Since the discovery of the association between abnormal growth and adverse pregnancy outcome, fetal growth has been the subject
of research. This has focused on unraveling pathophysiologic mechanisms that underlie growth restriction, identification of
factors associated with growth restriction, and prenatal detection of small for gestation (SGA) pregnancies. Since growth
restriction cannot be prevented or cured, studies have focused on detection of abnormal growth because antenatal detection
is thought to reduce adverse pregnancy outcome and perinatal death. Despite all efforts, the majority of SGA infants remain
undiagnosed until delivery. 50% of unanticipated stillbirths at term are attributed to SGA. Methods to detect SGA fetuses
include antenatal clinical examination, symphysis-fundal height measurement, and ultrasound biometry. In this thesis we investigate
the association between several risk factors and SGA, we compare two methods to express fetal growth, and discuss the relation
between antenatal SGA detection, timing of delivery and pregnancy outcome in SGA pregnancies.
If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let
the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible
and/or remove it from the website. Please Ask the Library, or send a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands.
You will be contacted as soon as possible.