- Ubiquitination in apoptosis signaling
- Award date
- 22 April 2014
- Number of pages
- Document type
- PhD thesis
- Faculty of Science (FNWI)
- Swammerdam Institute for Life Sciences (SILS)
- The work described in this thesis focuses on ubiquitination and protein degradation, with an emphasis on how these processes
regulate apoptosis signaling. More specifically, our aims were:
1. To increase the understanding of ubiquitin-mediated regulation of apoptosis signaling.
2. To identify the E3 ubiquitin ligase targeting the apoptosis protein tBidN for unconventional ubiquitination.
3. To delineate the role of N-terminal acetylation in protein degradation.
- Research conducted at: Universiteit van Amsterdam
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